Pentose Phosphate Pathway made simple. This pathway has two major jobs: Generate NADPH Produce ribose 5 phosphate NADPH protects cells from oxidative stress and supports fatty acid, cholesterol, steroid, nitric oxide, and respiratory burst Frontiers The Role of the Pentose Phosphate Pathway in Diabetes and Cancer Glutathione Pathways Pentose Phosphate Pathway Reactions in Photosynthesizing Cells Pentose Phosphate Pathway: ditki medical and biological sciences PENTOSE PHOSPHATE PATHWAY