The pentose phosphate pathway in health and disease Nature Metabolism A metabolic switch to the pentose phosphate pathway induces radiation resistance in pancreatic cancer Radiotherapy and Oncology Glucose metabolism begins with its transport into cells via GLUT transporters, where it is phosphorylated to glucose 6 phosphate (Glucose 6 P). This molecule can enter various pathways, including the pentose phosphate pathway or hexosamine biosynthesis. HMP also known as the Pentose phosphate pathway. Consists of two irreversible oxidative rxs followed by a series of reversible Lecture 21 Pentose Phosphate Pathway Flashcards Quizlet 6.3: The Pentose Phosphate Pathway Biology LibreTexts